About

The Cell Structure and Mechanobiology Group is where biology, physics and computing collide in a quest to derive mathematical principles that explain functional changes in cell dynamics and architecture in both healthy and disease states.

About

The Cell Structure and Mechanobiology Group is where biology, physics and computing collide in a quest to derive mathematical principles that explain functional changes in cell dynamics and architecture in both healthy and disease states.

Biology has provided an enormous body of descriptive data in its bid to understand the organism by first taking it apart, starting with anatomical descriptions and progressing through to organs, cells and molecules. These descriptions, however, do not necessarily explain the dynamic organisational capacity of cell-based life. At Melbourne School of Engineering, the Cell Structure and Mechanobiology Group is working to create new ways to integrate and analyse biological data. Their goal is to define dynamic principles that drive function-altering changes in cell and tissue architecture, including during disease progression. This ambitious initiative brings physics, advanced imaging technology, biochemistry, electrophysiology, mathematical modelling and machine learning together within a vibrant, intellectually stimulating, multi-disciplinary team. The goal is the development of dynamic simulations that explain changes to cellular systems, with models providing a new platform to test and develop new disease interventions.