Associate Professor Andrew Zalesky

  • Room: Level: 03 Room: 311
  • Building: Alan Gilbert Building
  • Campus: Parkville

Research interests

  • Network Science, Connectome Bioinformatics
  • Null Models, Network Inference, Permutation & Resampling
  • Schizophrenia, Diagnostic Biomarkers
  • Systems Neuroscience, Nerual Mass Models
  • Tractography, Connectome, Functional Connectivity, Neuroimaging

Personal webpage


I'm a researcher at the University of Melbourne, Australia. I am based at the Melbourne Neuropsychiatry Centre. I'm grateful to the NHMRC and ARC for supporting my research. I currently hold the NHMRC CDF. 

Recent publications

  1. Sarwar T, Kotagiri R, Zalesky A. Mapping connectomes with diffusion MRI: deterministic or probabilistic tractography?. Magnetic Resonance in Medicine. John Wiley & Sons. 2019, Vol. 81, Issue 2. DOI: 10.1002/mrm.27471
  2. Al-Amin M, Bradford DK, Sullivan RKP, Kurniawan ND, Moon Y, Han SH, Zalesky A, Burne THJ. Vitamin D deficiency is associated with reduced hippocampal volume and disrupted structural connectivity in patients with mild cognitive impairment. Human Brain Mapping. Wiley-Liss. 2019, Vol. 40, Issue 2. DOI: 10.1002/hbm.24380
  3. Lin H-Y, Cocchi L, Zalesky A, Lv J, Perry A, Tseng W-YI, Kundu P, Breakspear M, Gau SS-F. Brain-behavior patterns define a dimensional biotype in medication-naive adults with attention-deficit hyperactivity disorder. PSYCHOLOGICAL MEDICINE. Cambridge University Press. 2018, Vol. 48, Issue 14. DOI: 10.1017/S0033291718000028
  4. Tian Y, Zalesky A. Characterizing the functional connectivity diversity of the insula cortex: Subregions, diversity curves and behavior. NEUROIMAGE. Academic Press. 2018, Vol. 183. DOI: 10.1016/j.neuroimage.2018.08.055
  5. Fornito A, Zalesky A. Computational Approaches to Understanding Mental Dysfunction: Progress, Challenges, and New Frontiers. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 2018, Vol. 3, Issue 9. DOI: 10.1016/j.bpsc.2018.07.005
  6. Kamagata K, Zalesky A, Hatano T, Di Biase M, El Samad O, Saiki S, Shimoji K, Kumamaru KK, Kamiya K, Hori M, Hattori N, Aoki S, Pantelis C. Connectome analysis with diffusion MRI in idiopathic Parkinson's disease: Evaluation using multi-shell, multi-tissue, constrained spherical deconvolution. NEUROIMAGE-CLINICAL. Elsevier. 2018, Vol. 17. DOI: 10.1016/j.nicl.2017.11.007
  7. Fullerton JM, Klauser P, Lenroot RK, Shaw AD, Overs B, Heath A, Cairns MJ, Atkins J, Scott R, Schofield PR, Shannon Weickert C, Pantelis C, Fornito A, Whitford TJ, Weickert T, Zalesky A. Differential effect of disease-associated ST8S/A2 haplotype on cerebral white matter diffusion properties in schizophrenia and healthy controls. TRANSLATIONAL PSYCHIATRY. Nature Publishing Group. 2018, Vol. 8, Issue 1. DOI: 10.1038/s41398-017-0052-z
  8. Kale P, Zalesky A, Gollo LL. Estimating the impact of structural directionality: How reliable are undirected connectomes?. NETWORK NEUROSCIENCE. MIT Press. 2018, Vol. 2, Issue 2. DOI: 10.1162/netn_a_00040
  9. Hoffmann C, Van Rheenen T, Mancuso S, Zalesky A, Bruggemann J, Lenroot RK, Sundram S, Shannon Weickert C, Weickert T, Pantelis C, Cropley V, Bousman C. Exploring the moderating effects of dopaminergic polymorphisms and childhood adversity on brain morphology in schizophrenia-spectrum disorders. PSYCHIATRY RESEARCH-NEUROIMAGING. Elsevier Ireland. 2018, Vol. 281. DOI: 10.1016/j.pscychresns.2018.09.002
  10. Gollo LL, Roberts JA, Cropley V, Di Biase M, Pantelis C, Zalesky A, Breakspear M. Fragility and volatility of structural hubs in the human connectome. NATURE NEUROSCIENCE. Nature America. 2018, Vol. 21, Issue 8. DOI: 10.1038/s41593-018-0188-z
  11. Laskaris L, Zalesky A, Shannon Weickert C, Di Biase M, Chana G, Baune BT, Bousman C, Nelson C, McGorry P, Everall I, Pantelis C, Cropley V. Investigation of peripheral complement factors across stages of psychosis. Schizophrenia Research. Elsevier Science. 2018. DOI: 10.1016/j.schres.2018.11.035
  12. Van Dellen E, Sommer IE, Bohlken MM, Tewarie P, Draaisma L, Zalesky A, Di Biase M, Brown JA, Douw L, Otte WM, Mandl RCW, Stam CJ. Minimum spanning tree analysis of the human connectome. HUMAN BRAIN MAPPING. Wiley-Liss. 2018, Vol. 39, Issue 6. DOI: 10.1002/hbm.24014
  13. Pedersen M, Zalesky A, Omidvarnia A, Jackson G. Multilayer network switching rate predicts brain performance. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. National Academy of Sciences. 2018, Vol. 115, Issue 52. DOI: 10.1073/pnas.1814785115
  14. Seguin C, Van Den Heuvel MP, Zalesky A. Navigation of brain networks. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. National Academy of Sciences. 2018, Vol. 115, Issue 24. DOI: 10.1073/pnas.1801351115
  15. Bousman C, Cropley V, Klauser P, Hess JL, Pereira A, Idrizi R, Bruggemann J, Mostaid M, Lenroot R, Weickert T, Glatt SJ, Everall I, Sundram S, Zalesky A, Shannon Weickert C, Pantelis C. Neuregulin-1 (NRG1) polymorphisms linked with psychosis transition are associated with enlarged lateral ventricles and white matter disruption in schizophrenia. PSYCHOLOGICAL MEDICINE. Cambridge University Press. 2018, Vol. 48, Issue 5. DOI: 10.1017/S0033291717002173

View a full list of publications on the University of Melbourne’s ‘Find An Expert’ profile