Professor David Grayden

  • Room: Level: 01 Room: 105
  • Building: 203 Bouverie St
  • Campus: Parkville

Research interests

  • Bionic Ear (Speech processing, bionics, neuroengineering)
  • Bionic Eye (Vision processing, bionics, neuroengineering)
  • Brain-Machine Interfaces (Brain-computer interfaces, bionics, neuroengineering)
  • Computational Neuroscience (Neural modelling, neural learning, neural dynamics, neuroengineering)
  • Epilepsy (Prediction of seizures, seizure control, neuroengineering)

Personal webpage


Professor David B. Grayden is Clifford Chair of Neural Engineering in the Department of Biomedical Engineering, Melbourne School of Engineering and the Graeme Clark Institute for Biomedical Engineering. Prof Grayden's main research interests are in understanding how the brain processes information, how best to present information to the brain using medical bionics, such as the bionic ear and bionic eye, and how to record information from the brain, such as for brain-machine interfaces. He is also conducting research in epileptic seizure prediction and electrical stimulation to prevent or stop epileptic seizures, and in electrical stimulation of the vagus nerve to control inflammatory bowel disease. He has research linkages with the Bionics Institute, St Vincent's Hospital Melbourne, Royal Melbourne Hospital, University of South Australia, Florey Institute for Neuroscience and Mental Health, and IBM Research. Prof Grayden teaches in the Bioengineering and Biomedical Engineering programs. He teaches BioDesign Innovation and contributes to the Neuroscience Research Training course modules. Research interests: Computational Neuroscience Epilepsy Audition, Speech and Bionic Ear Design Vision and Bionic Eye Design Brain-Machine Interfaces Electroceuticals

Recent publications

  1. Spencer M, Kameneva T, Grayden D, Meffin H, Burkitt A. Global activity shaping strategies for a retinal implant. JOURNAL OF NEURAL ENGINEERING. Institute of Physics Publishing. 2019, Vol. 16, Issue 2. DOI: 10.1088/1741-2552/aaf071
  2. John S, Apollo N, Opie N, Rind G, Ronayne S, May C, Oxley T, Grayden D. In Vivo Impedance Characterization of Cortical Recording Electrodes Shows Dependence on Electrode Location and Size. IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING. IEEE - Institute of Electrical and Electronic Engineers. 2019, Vol. 66, Issue 3. DOI: 10.1109/TBME.2018.2854623
  3. Barutchu A, Toohey S, Shivdasani M, Fifer JM, Crewther S, Grayden D, Paolini A. Multisensory perception and attention in school-age children. JOURNAL OF EXPERIMENTAL CHILD PSYCHOLOGY. Academic Press. 2019, Vol. 180. DOI: 10.1016/j.jecp.2018.11.021
  4. Lian Y, Grayden D, Kameneva T, Meffin H, Burkitt A. Toward a Biologically Plausible Model of LGN-V1 Pathways Based on Efficient Coding. FRONTIERS IN NEURAL CIRCUITS. Frontiers Research Foundation. 2019, Vol. 13. DOI: 10.3389/fncir.2019.00013
  5. Yoo P, John S, Farquharson S, Cleary J, Wong YT, Ng A, Mulcahy C, Grayden D, Ordidge R, Opie N, O'Brien T, Oxley T, Moffat B. 7T-fMRI: Faster temporal resolution yields optimal BOLD sensitivity for functional network imaging specifically at high spatial resolution. NEUROIMAGE. Academic Press. 2018, Vol. 164. DOI: 10.1016/j.neuroimage.2017.03.002
  6. Zarei Eskikand P, Kameneva T, Ibbotson M, Burkitt A, Grayden D. A biologically-based computational model of visual cortex that overcomes the X-junction illusion. NEURAL NETWORKS. Pergamon Press. 2018, Vol. 102. DOI: 10.1016/j.neunet.2018.02.008
  7. Oxley T, Opie N, Rind G, Liyanage K, John S, Ronayne S, McDonald A, Dornom A, Lovell T, Mitchell P, Bennett I, Bauquier S, Warne L, Steward C, Grayden D, Desmond P, Davis S, O'Brien T, May C. An ovine model of cerebral catheter venography for implantation of an endovascular neural interface. JOURNAL OF NEUROSURGERY. American Association of Neurological Surgeons. 2018, Vol. 128, Issue 4. DOI: 10.3171/2016.11.JNS161754
  8. Ahmadizadeh S, Karoly P, Nesic D, Grayden D, Cook M, Soudry D, Freestone D. Bifurcation analysis of two coupled Jansen-Rit neural mass models. PLOS ONE. Public Library of Science. 2018, Vol. 13, Issue 3. DOI: 10.1371/journal.pone.0192842
  9. Esler T, Maturana M, Kerr R, Grayden D, Burkitt A, Meffin H. Biophysical basis of the linear electrical receptive fields of retinal ganglion cells. JOURNAL OF NEURAL ENGINEERING. Institute of Physics Publishing. 2018, Vol. 15, Issue 5. DOI: 10.1088/1741-2552/aacbaa
  10. Kameneva T, Meffin H, Burkitt A, Grayden D. Bistability in Hodgkin-Huxley-type equations. 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). Institute of Electrical and Electronics Engineers. 2018, Vol. 2018. DOI: 10.1109/EMBC.2018.8513233
  11. Karoly P, Goldenholz DM, Freestone D, Moss RE, Grayden D, Theodore WH, Cook M. Circadian and circaseptan rhythms in human epilepsy: a retrospective cohort study. LANCET NEUROLOGY. The Lancet Publishing Group. 2018, Vol. 17, Issue 11. DOI: 10.1016/S1474-4422(18)30274-6
  12. Spencer M, Meffin H, Burkitt A, Grayden D. Compensation for Traveling Wave Delay Through Selection of Dendritic Delays Using Spike-Timing-Dependent Plasticity in a Model of the Auditory Brainstem. FRONTIERS IN COMPUTATIONAL NEUROSCIENCE. Frontiers Research Foundation. 2018, Vol. 12. DOI: 10.3389/fncom.2018.00036
  13. Nurse E, John S, Freestone D, Oxley T, Ung H, Berkovic S, O'Brien T, Cook M, Grayden D. Consistency of Long-Term Subdural Electrocorticography in Humans. IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING. IEEE - Institute of Electrical and Electronic Engineers. 2018, Vol. 65, Issue 2. DOI: 10.1109/TBME.2017.2768442
  14. Gerboni G, John S, Ronayne S, Rind G, May C, Oxley T, Grayden D, Opie N, Wong Y. Cortical Brain Stimulation with Endovascular Electrodes.. Conf Proc IEEE Eng Med Biol Soc. Institute of Electrical and Electronics Engineers. 2018, Vol. 2018. DOI: 10.1109/EMBC.2018.8512971
  15. Opie N, John S, Rind G, Ronayne S, May C, Grayden D, Oxley T. Effect of Implant Duration, Anatomical Location and Electrode Orientation on Bandwidth Recorded with a Chronically Implanted Endovascular Stent-Electrode Array. 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). Institute of Electrical and Electronics Engineers. 2018, Vol. 2018-July. DOI: 10.1109/EMBC.2018.8512385.

View a full list of publications on the University of Melbourne’s ‘Find An Expert’ profile