The Cell Systems and Mechanobiology Lab creates physiologically realistic computational models of cells and organs to advance healthcare.
We create physiologically realistic computational models of cells and organs to advance healthcare. Our "digital-twin" models and physiology-informed algorithms advance basic understanding of how biological systems work and inform decision making in clinical and pharmaceutical applications.
Biology has provided an enormous body of descriptive data in its bid to understand the organism. But these descriptions do not explain the dynamic organisational capacity of cell-based life.
At the Faculty of Engineering and Information Technology, the Cell Systems and Mechanobiology Lab is applying engineering sciences to create new ways to integrate and analyse biological data. We bring advanced imaging technology, biomechanics, systems biology, mechanobiology, mathematical modelling and artificial intelligence together within a vibrant, intellectually stimulating, multi-disciplinary team to solve fundamental mysteries of how biology works. We apply our algorithms and technologies to solve disease treatment, diagnosis and drug discovery applications.
Our goal is the development of dynamic simulations that explain changes to cellular systems, with models providing a new platform to test and develop new disease interventions.